Technology

Publications

Prolias Authors

Sarkar, J., Soukharev, S., Lathrop, J.T., and Hammond, D. J. (2007), Functional identifaction f Novel Activities: Activity-based Selection of Proteins from Complete Proteomes, Anal. Biochem.365:91-102.

Lathrop, J.T., Fijalkowska, I and Hammond, D. J. (2007), The Bead Blot: A method for identifying ligand-protein and protein-protein interactions using combinatorial libraries of peptide ligands, Anal. Biochem.361:65-76.

Fortis, F.; Guerrier,L; Areces,L.B.; Antonioli,P.; Hayes,T. K.; Carrick, K.; Hammond D. J.; Boschetti, E.; Righetti, P. G. (2006). A new approach for the detection and identification of protein impurities using combinatorial solid phase ligand libraries, J. Prot. Res. 5:2577-2585.

Gregori, L.; Gurgel, P.V.; Lathrop, J.T.; Edwardson, P.; Lambert, B.C.; Carbonell, R.G.; Burton, S.J.; Hammond, D.J.; Rohwer, R.G. (2006). Reduction of the endogenous infectivity present in blood by adsorption to selective affinity resins. Lancet 368:2226-2230.

Gregori, L.; Lambert, B. C.; Gurgel, P. V.; Gheorghiu, L.; Edwardson, P.; Lathrop, J. T.; MacAuley, C.; Carbonell, R. G.; Burton, S. J.; Hammond, D.; Rohwer, R. G. (2006). Reduction of TSE infectivity from red blood cells using prion protein affinity ligands. Transfusion 46: 1152-1161.

Hammond, D. J. and Lathrop, J. (2005). FIoNA: The Discovery of Trace Therapeutic Proteins from Complex Biological Materials. Innovations in Pharm. Tech. 17: 38-41.

Thulasiraman, V.; Lin, S.; Gheorghiu, L.; Lathrop, J.; Lomas, L.; Hammond, D.; Boschetti, E. (2005). Reduction of the concentration differential of proteins in biological liquids using a library of combinatorial ligands. Electrophoresis 26(18):3561-3571.

Soukharev S. and Hammond, D.J. (2004). A fluorogenic substrate for detection of organophosphatase activity. Analytical Biochemistry, 327: 140-148.

Additional publications addressing Prolias technology

Righetti, P.G. and Boschetti, E. (2007) Sherlock Holmes and the proteome - a detective story. FEBS J. 274:897-905.

Fortis, F.; Guerrier, L.; Righetti, P.G.; Antonioli, P.; Boschetti, E. (2006) A new approach for the removal of protein impurities from purified biologicals using combinatorial solid-phase ligand libraries Electrophoresis 27:3018-3027

Guerrier, L.; Thulasiraman, V.; Castagna, A.; Fortis, F.; Lin, S.; Lomas, L.; Righetti, P. G.; Boschetti, E. (2006) Reducing protein concentration range of biological samples using solid-phase ligand libraries J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 833: 33-40.

Castagna, A.; Cecconi,D.; Sennels,L.; Rappsilber,J.; Guerrier,L.; Fortis,F.; Boschetti,E.; Lomas,L.; Righetti,P. G. (2005). Exploring the hidden human urinary proteome via ligand library beads, J. Prot. Res. 4: 1917-1930

Righetti, P.G.; Boschetti,E.; Lomas,L.; Citterio,A. (2006). Protein Equalizer Technology: the quest for a "democratic proteome", Proteomic, 6: 3980-3992.

Righetti, P.G.; Castagna,A.; Antonioli,P.; Boschetti,E. (2005). Pre-fractionation techniques in proteome analysis: the mining tools of the third millennium. Electrophoresis 26: 3561-3571.

Righetti, P.G.; Castagna,A,; Antonucci,F,; Piubelli,C.; Cecconi,D.; Campostrini,N.; Rustichelli,C.; Antonioli,P.; Zanusso,G.; Monaco,S.; Lomas,L.; Boschetti,E. (2005) Proteome analysis in the clinical chemistry laboratory: Myth or reality? Clinica chemical acta 357: 123-139

Reviews

Lathrop, J.T., Hayes, T.K., Carrick, K., Hammond, D.J. (2005). "Rarity Holds a Charm": Evaluation of trace proteins in plasma and serum (invited review). Expert Reviews of Proteomics 2: 393-406.

Lathrop, J.T., Anderson, N.L., Anderson, N., Hammond, D.J. (2003). Therapeutic potential of the human proteome. Current Opinion in Molecular Therapeutics 5: 250-257

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